Immunogenomics of colorectal cancer response to immune checkpoint blockade: TCRseq

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DOI10.5281/zenodo.3744371Zenodo3744371MaRDI QIDQ6679384FDOQ6679384

Dataset published at Zenodo repository.

Charles Swanton, Susan John, Kai-Keen Shiu, Peter Parker, Maise al Bakir, Lorena Benedetti, Banafshe Larijani, Petrov Nedyalko, Michele Bortolomeazzi, Damjan Temelkovski, Sophia Ward, Subin Choi, Jo Spencer, James Miles, Manuel Rodriguez-Justo, Francesca D Ciccarelli, Mohamed Reda Keddar, Gareth A. Wilson, Todd Katrina, Lucia Montorsi

Publication date: 8 April 2020



Immunogenomics of colorectal cancer response to immune checkpoint blockade TCR-seq data supporting the paper: Immunogenomics of colorectal cancer response to immune checkpoint blockade Both files were downloaded from the Adaptive Biotechnologies immunoSeq Analyzer portal on 17/12/2019. RearrangementDetails_12-17-2019_9-06-47_AM.tsv: contains the detailed productive rearrangement data for all 28 regions sequenced. For each region, data includes the nucleotide sequence, the amino acid sequence, the V, D, and J gene and allele identifications and the frequency of all the productive rearrangements in that region. SampleOverview_12-17-2019_9-03-56_AM.tsv: contains the region-level data that includes absolute number of rearrangements and productive rearrangements and productive clonality for all 28 regions sequenced.







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