Input data for the case study reported in "DREAM: an R package for druggability evaluation of human complex diseases".
DOI10.5281/zenodo.7962332Zenodo7962332MaRDI QIDQ6682423FDOQ6682423
Dataset published at Zenodo repository.
Federico Antonio, Angela Serra, Alisa Pavel, Dario Greco, Lena Möbus, Giusy del Giudice, Fratello Michele
Publication date: 23 May 2023
Copyright license: Creative Commons Attribution 4.0 International
The data included in this record constituted the input for the case study reported in the manuscript DREAM: an R package for druggability evaluation of human complex diseases, by Antonio Federico, Michele Fratello, Alisa Pavel, Lena Mbus, Giusy del Giudice, Angela Serra, Dario Greco. The data derive from transcriptomics experiments executed on lesional skin from atopic dermatitis patients and unaffected skin counterparts. The data consists of two files in .txt format reporting gene expression data in tabular format, where on the rows are reported genes and on the columns are reported samples. The data is an aggregated and batch-corrected collection of datasets originally downloaded by Gene Expression Omnibus (GEO, https://www.ncbi.nlm.nih.gov/geo/). The file GE_Mic_AD_Pamr_MAARS.txt reports gene expression estimates of lesional skin of atopic dermatitis patients, while the file GE_Mic_AD_Pamr_nl_MAARS.txt reports gene expression estimates of non-lesional skin of atopic dermatitis patients.
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