Curated and harmonised transcriptomics datasets of interstitial lung disease patients

DOI10.5281/zenodo.10692129Zenodo10692129MaRDI QIDQ6682431FDOQ6682431

Dataset published at Zenodo repository.

Simo Inkala, Antonio Federico, Dario Greco, Angela Serra

Publication date: 22 February 2024

Copyright license: Creative Commons Attribution 4.0 International

Description

The datasets uploaded within this record contain transcriptomics data of interstitial lung disease patients retrieved from the NCBI Gene Expression Omnibus and European Nucleotide Archive (ENA) repositories. Overall, we retrieved 30 transcriptomics datasets, produced through both DNA microarrays and RNA-Sequencing technologies, along with relative meta-data tables. After data collection, all the datasets underwent meta-data curation and harmonisation, data quality check, and pre-processing with standardised procedures. Beside, data model was created in order to homogenise the phenotypic data enabling the comparability across the datasets. In addition, for every study included in this data release we provide tables of differentially expressed genes and co-expression network models of IPF samples and healthy counterparts deriving from both RNA-seq and DNA microarrays.

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