Preexisting memory CD4 T cells in naïve individuals confer robust immunity upon vaccination
DOI10.5281/zenodo.3989144Zenodo3989144MaRDI QIDQ6683841FDOQ6683841
Dataset published at Zenodo repository.
Pieter Meysman, Esther Bartholomeus, Geert Mortier, Nina Keersmaekers, Arvid Suls, Viggo van Tendeloo, Hilde Jansens, Aisha Souquette, Hans de Reu, Pierre van Damme, Philippe Beutels, George Elias, Benson Ogunjimi, Kris Laukens, Nicolas de Neuter, Paul G Thomas, Eva Lion, Evelien Smits
Publication date: 17 August 2020
Copyright license: Creative Commons Attribution 4.0 International
Data set accompanying the publication Preexisting memory CD4 T cells in nave individuals confer robust immunity upon vaccination. In this study, we utilize high-throughput sequencing to profile the memory CD4 TCR repertoire and track vaccine-specific and epitope-specific TCR clonotypes following thede novoadministration of hepatitis B(HepB)vaccinein healthy HepB-nave individuals. The data set is comprised out of the following parts: repTCRb: Folder containing CD4+ TCR repertoire data from volunteers. Some of these samples are also available in ImmuneAccess (https://clients.adaptivebiotech.com/pub/deneuter-2018-cmvserostatus). peptideTCRab: Folder containing peptide-specific or peptide-pool-specific TCR data df_all: Meta and FC data for samples and volunteers freqCD154: CD154-based group definitions groups.csv: Group definitions used for classes
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