A kinetics-based model of hematopoiesis reveals extrinsic regulation of skewed lineage output from stem cells - data repository
DOI10.5281/zenodo.14497706Zenodo14497706MaRDI QIDQ6691467FDOQ6691467
Dataset published at Zenodo repository.
Esther Rodriguez-Correa, Daniel Huebschmann, Anastasia Sedlmeier, Florian Grünschläger, Simon Haas, Tamar Nizharadze
Copyright license: Creative Commons Attribution 4.0 International
Single-cell RNA sequencing data from five single-HSC-derived murine hematopoietic systems, as well as two polyclonal controls. The resulting clonally-resolved hematopoietic bone marrow atlas (scBM_atlas.rds) consists of 76,863 high-quality cells and covers all major hematopoietic cell types, including differentiation tracks (slingshot.rds) from the most immature HSCs to all lineage-committed progenitors (HSPCs.rds) and their continued maturation into blood and immune cells.
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