High-throughput sequencing of Trastuzumab CDRH3 variant yeast display library

DOI10.5281/zenodo.10831512Zenodo10831512MaRDI QIDQ6693093FDOQ6693093

Dataset published at Zenodo repository.

Khang le Quy, Fridtjof Lund-Johansen, Victor Greiff, Andrei Slabodkin, Brij Mehta

Copyright license: Creative Commons Attribution 4.0 International

Description

High-throughput sequencing dataset for Trastuzumab CDRH3 variant library. Each library sample is created from flow cytometry-sorted yeast cells displaying variant Trastuzumab on the cell surface and categorized based on binding affinity with HER2: Sample 1: Tz variants strong binders Sample 2: Tz variants intermediate binders Sample 3: Tz variants weak binders All processed data and weights from 'Baselining the Buzz.Trastuzumab-HER2 Affinity, and Beyond!' can be found in data.zip

This page was built for dataset: High-throughput sequencing of Trastuzumab CDRH3 variant yeast display library