CollecTRI Data for Investigation of SETBP1 gene expression and transcription factor activity across human tissues

DOI10.5281/zenodo.8222799Zenodo8222799MaRDI QIDQ6694888FDOQ6694888

Dataset published at Zenodo repository.

Brittany N. Lasseigne, Elizabeth J. Wilk, Amanda D. Clark, Timothy C. Howton, Jordan H. Whitlock

Publication date: 7 August 2023

Copyright license: Creative Commons Attribution 4.0 International

Description

Here we provide the human CollecTRI prior (accessed May 2023) for inference of TF activity across 31 GTEx tissues using multivariate linear modeling method decoupleR. The `human_prior_tri.csv` includes 1,178 unique TFs (referred to as the source) that target 6,627 unique genes (referred to as targets) to give us 42,595 interactions in the CollecTRI prior input. Interactions are represented as a + or - 1 (mor).

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