Adult neurogenesis improves spatial information encoding in the mouse hippocampus - Irr+EE

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Dataset:6707020



DOI10.5281/zenodo.10933615Zenodo10933615MaRDI QIDQ6707020FDOQ6707020

Dataset published at Zenodo repository.

J. Tiago Gonçalves, Evan A Huaman, Solen Gokhan, Sunaina S Martin, Kelsey McDermott, M. Agustina Frechou, Wolfgang Tomé, Ruben Coen-Cagli

Publication date: 5 April 2024

Copyright license: Creative Commons Attribution 4.0 International



In vivo two-photon imaging dataset for Frechou et al. "Adult neurogenesis improves spatial information encoding in the mouse hippocampus" This dataset includes data from mice that were irradiated to ablate adult neurogenesis and housed in an enriched environment (Irr+EE). For each recording we included raw imaging data consisting of: Individual frames (.tif files) from 3 consecutive 3 min Ca2+ imaging movies (which were concatenated for analysis) Microscope settings metadata (Experiment.xml) Mouse location data (Episode001.h5 in SyncData folder) containing rotary encoder and RFID data Some analyzed data is also included: Suite2p analysis data (Suite2p folder) fluorescence.npycontains raw fluorescence data (the F output of Suite2p data extraction). Rows are individual cells and columns are frames (i.e. timepoints) acquired at 15.253 Hz. positions.npycontains the position of the mouse on the treadmill belt indexed from 0 to 100. Both NumPy(.npy) files are the output of the Preprocessing.py code, part of the analysis pipeline used for data analysis in the original publication, which can be found at https://github.com/GoncalvesLab/Frechou-et-al-Neurogenesis All imaged mice were female. Refer to the original publication for additional information.







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