A cerebellar internal model calibrates a feedback controller involved in sensorimotor control
DOI10.5281/zenodo.5052785Zenodo5052785MaRDI QIDQ6707508FDOQ6707508
Dataset published at Zenodo repository.
Daniil A. Markov, Andreas M. Kist, Luigi Petrucco, Ruben Portugues
Publication date: 1 July 2021
Copyright license: Creative Commons Attribution 4.0 International
This upload contains datasets from the manuscript by Markov et al., 2021 A cerebellar internal model calibrates a feedback controller involved in sensorimotor control (preprint here; thecode used to acquire and process these data can be found here). The datasets are organized in the following zip folders: behavioral_data.zip contains data from acute reaction and long-term adaptation experiments for wild-type control, treatment control, and Purkinje-cell-ablated zebrafish larvae feedback_control_model.zip contains parameters of the model after fitting it to the data acquired during theacute reaction experiment. PC_ablation_quantification.zip contains confocal images of the cerebella of zebrafish larvae before and after pharmaco-genetic ablation of Purkinje cells. reference_brain_stacks.zip contains z-stacks used for anatomical registration of the functional imaging data whole_brain_imaging_inetgrators.zip contains whole-brain light-sheet data acquired while zebrafish larvae were performing optomotor response to forward moving grating. This dataset was used to identify sensory integrators in the larval zebrafish brain PC_imaging_long_term_adaptation.zip contains light-sheet recordings of Purkinje cell activity acquired during long-term adaptation to laggedvisual feedback. This dataset was used to identify signatures of internal models in the Purkinje cell activity. whole_brain_imaging_long_term_adaptation.zip contains whole-brain light-sheet recordings during long-term adaptation to laggedvisual feedback. This dataset was used to study correlates of the long-term adaptation in the entire brain (such as change in sensory integration time constants). For any question about the data, please write atruben.portugues@tum.deor daniil.markov@charite.de.
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