The spatio-temporal program of liver zonal regeneration
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We performed mouse bulk liver mRNA sequencing (mcSCRBseq, Bagnoli et al., 2018),single-cell RNA seq (Feature Barcode 10x) and spatial transcriptomics (10x Visium)of hepatocytes and non-parenchymal cells (NPCs) at several time points along the time course of Acetaminophen (APAP)-induced liver damage and regeneration to identify spatio-temporal dynamics of liver regeneration.
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