Deconvolution analysis of spatial transcriptomics by multiplicative-additive Poisson-gamma models

DOI10.1214/24-AOAS1953MaRDI QIDQ6665544zbMATH OpenFDO

Authors Yutong Luo, Joan E. Bailey-Wilson, Christopher Albanese, Ruzong Fan

Publication date 17 January 2025

Published in The Annals of Applied Statistics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1214/24-AOAS1953

zbMATH Keywords

cell type expression patternsdeconvolution analysismixed effect multiplicative-additive Poisson-gamma modelsscRNA-seqspatial transcriptomicsls

Mathematics Subject Classification ID

Applications of statistics (62Pxx)

Cites work

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• Poisson approximation and the Chen-Stein method. With comments and a rejoinder by the authors
• Small-sample estimation of negative binomial dispersion, with applications to SAGE data
• Two moments suffice for Poisson approximations: The Chen-Stein method

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