Diallelic multilocus model of neutral genes

DOI10.1007/BF00275887MaRDI QIDQ1090641zbMATH OpenOpenAlexWikidataFDO

Authors Morihiro Notohara

Publication date 1987

Published in Journal of Mathematical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1007/bf00275887

zbMATH Keywords

momentsSpectral analysisgenerating functionsdistributionsfinite populationlinkage disequilibriumRandom genetic driftgenotype frequenciesnumber of segregating sitesbackward diffusion equationcompletely linked loci additive modeldiffusion model approximationdiploid multilocus diallelic model of neutral genesDNA nucleotide sequencespolygenic traitreciprocal mutationtransient and steady state

Mathematics Subject Classification ID

Applications of Brownian motions and diffusion theory (population genetics, absorption problems, etc.) (60J70) Genetics and epigenetics (92D10) Diffusion processes (60J60)

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Cites work

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• scientific article; zbMATH DE number 3349081 (Why is no real title available?)
• A class of degenerate diffusion processes occurring in population genetics
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• Coherent random walks arising in some genetical models
• Effect of overall phenotypic selection on genetic change at individual loci.
• Eigenanalysis for the Kolmogorov backward equation for the neutral multi- allelic model
• Estimation of the neutral mutation rate in a finite population from DNA sequence data
• Genetic identity between populations when mutation rates vary within and across loci
• On the number of segregating sites in genetical models without recombination
• Possibility of extensive neutral evolution under stabilizing selection with special reference to nonrandom usage of synonymous codons.
• Role of very slightly deleterious mutations in molecular evolution and polymorphism
• The infinitely-many-sites model as a measure-valued diffusion
• The lattice models of neutral multi-alleles in population genetics theory
• The number of alleles and segregating sites in a sample from the infinite-alleles model
• Wandering distributions and the electrophoretic profile
• Wandering phenomena in infinite-allelic diffusion models

Cited in

(9)

• scientific article; zbMATH DE number 4037661 (Why is no real title available?)
• Drift and mutation with a finite number of allelic states
• Existence of steady-state probability distributions in multilocus models for genotype evolution
• Analysis of a population genetics model with mutation, selection, and pleiotropy
• The use of sample genealogies for studying a selectively neutral m-loci model with recombination
• Multilocus models in the infinite island model of population structure
• A model of dynamics of mutation, genetic drift and recombination in DNA-repeat genetic loci
• Linkage disequilibrium of extranuclear genes under neutral mutations and random genetic drift
• A model of electrophoretic variation: Finite populations and finite numbers of mutable sites

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