Efficient experimental design for dose response modelling

DOI10.1080/02664763.2021.1880556MaRDI QIDQ5861231zbMATH OpenOpenAlexFDO

Authors Jack Silcox, Timothy E. O'Brien

Publication date 4 March 2022

Published in Journal of Applied Statistics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1080/02664763.2021.1880556

zbMATH Keywords

bioassayefficiencygoodness of fitlogistic regressionmedian lethal doserelative potency

Mathematics Subject Classification ID

General nonlinear regression (62J02) Generalized linear models (logistic models) (62J12) Optimal statistical designs (62K05) Applications of statistics (62Pxx)

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Cites work

• Efficient geometric and uniform design strategies for sigmoidal regression models: theory and methods
• scientific article; zbMATH DE number 3734989 (Why is no real title available?)
• scientific article; zbMATH DE number 3617410 (Why is no real title available?)
• scientific article; zbMATH DE number 2012514 (Why is no real title available?)
• scientific article; zbMATH DE number 3361160 (Why is no real title available?)
• Optimum experimental designs, with SAS
• The Equivalence of Two Extremum Problems

Cited in

(10)

• Optimal experimental designs for estimating the drug combination index in toxicology
• Optimal designs for estimating critical effective dose under model uncertainty in a dose response study
• Experimental designs for the estimation of the concentration curve and the AUC
• scientific article; zbMATH DE number 1917647 (Why is no real title available?)
• A pool-adjacent-violators-algorithm approach to detect infinite parameter estimates in one-regressor dose-response models with asymptotes
• Summarizing EC50 estimates from multiple dose-response experiments: a comparison of a meta-analysis strategy to a mixed-effects model approach
• Editorial to the special issue: Recent statistical methods for data analysis, applied economics, business \& finance
• Optimal designs for dose-finding experiments in toxicity studies
• Nonlinear regression modelling: a primer with applications and caveats
• Optimal designs for discriminating between dose-response models in toxicology studies

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