ememax

MaRDI QIDQ7379832CRANFDO

Authors Jiangshan Zhang, Vivek Pradhan, Yuxi Zhao

Last update 17 March 2026

Copyright license MIT license, File License

Software version identifier 0.1.0

Description

Provides estimation utilities for binary Emax dose-response models. Includes Expectation-Maximization based maximum likelihood estimation when the binary response is missing, as well as bias-reduced estimators including Jeffreys-penalized likelihood, Firth-score, and Cox-Snell corrections.The methodology is described in Zhang, Pradhan, and Zhao (2025) <doi:10.1177/09622802251403356> and Zhang, Pradhan, and Zhao (2026) <doi:10.1080/10543406.2026.2627387>.

Cites work

• Evaluating bias reduction methods in binary Emax model for reliable dose-response estimation
• Robust Emax model fitting: Addressing nonignorable missing binary outcome in dose–response analysis

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