ewoc

MaRDI QIDQ137366CRANFDO

Authors Marcio A. Diniz

Last update 31 August 2026

Copyright license GNU General Public License, version 2.0, GNU General Public License, version 3.0

Software version identifier 0.3.0, PACKAGES.rds, 0.1.0, 0.2.0, 0.3.1

Description

An implementation of a variety of escalation with overdose control designs introduced by Babb, Rogatko and Zacks (1998) <doi:10.1002/(SICI)1097-0258(19980530)17:10%3C1103::AID-SIM793%3E3.0.CO;2-9>. It calculates the next dose as a clinical trial proceeds and performs simulations to obtain operating characteristics.

Cites work

• Cancer phase I clinical trials: efficient dose escalation with overdose control

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