Fast simulation of lipid vesicle deformation using spherical harmonic approximation
From MaRDI portal
PDEs in connection with biology, chemistry and other natural sciences (35Q92) Spectral, collocation and related methods for initial value and initial-boundary value problems involving PDEs (65M70) Computational methods for problems pertaining to biology (92-08) Biochemistry, molecular biology (92C40)
Abstract: Lipid vesicles appear ubiquitously in biological systems. Understanding how the mechanical and intermolecular interations deform vesicle membrane is a fundamental question in biophysics. In this article we developed a fast algorithm to compute the surface configurations of lipid vesicles by introducing the surface harmonic functions to approximate the surfaces. This parameterization of the surfaces allows an analytical computation of the membrane curvature energy and its gradient for the efficient minimization of the curvature energy using a nonlinear conjugate gradient method. Our approach drastically reduces the degrees of freedom for approximating the membrane surfaces compared to the previously developed finite element and finite difference methods. Vesicle deformations with a reduced volume larger than 0.65 can be well approximated by using as small as 49 surface harmonic functions. The method thus has a great potential to reduce the computational expense of tracking multiple vesicles which deform for their interaction with external fields.
Recommendations
- 3D vesicle dynamics simulations with a linearly triangulated surface
- Simulating the deformation of vesicle membranes under elastic bending energy in three dimensions
- A level set projection model of lipid vesicles in general flows
- A fast algorithm for simulating vesicle flows in three dimensions
- Computing the dynamics of biomembranes by combining conservative level set and adaptive finite element methods
Cited in
(6)- Efficient linear, fully-decoupled and energy stable numerical scheme for a variable density and viscosity, volume-conserved, hydrodynamically coupled phase-field elastic bending energy model of lipid vesicles
- A general computational framework for the dynamics of single- and multi-phase vesicles and membranes
- Efficient energy stable scheme for volume-conserved phase-field elastic bending energy model of lipid vesicles
- Precise calculation of the local pressure tensor in Cartesian and spherical coordinates in LAMMPS
- Simulation of multiscale hydrophobic lipid dynamics via efficient integral equation methods
- Coarse-grained methods for heterogeneous vesicles with phase-separated domains: elastic mechanics of shape fluctuations, plate compression, and channel insertion
This page was built for publication: Fast simulation of lipid vesicle deformation using spherical harmonic approximation
Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q5372589)
