Fiber direction estimation, smoothing and tracking in diffusion MRI

DOI10.1214/15-AOAS880MaRDI QIDQ125183zbMATH OpenWikidataFDO

Authors Raymond K. W. Wong, Thomas C. M. Lee, Debashis Paul, Jie Peng, Alzheimer’S Disease Neuroimaging Initiative, Debashis Paul, Jie Peng, Raymond Wong, Thomas C. M. Lee

Publication date 1 September 2016

Published in The Annals of Applied Statistics (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/1406.0581

zbMATH Keywords

Alzheimer's Disease Neuroimaging Initiative (ADNI)diffusion tensor imagingdirection smoothingfiber trackingmulti-tensor modeltractography

Mathematics Subject Classification ID

Applications of statistics to biology and medical sciences; meta analysis (62P10) Image analysis in multivariate analysis (62H35) Biomedical imaging and signal processing (92C55)

Abstract: Diffusion magnetic resonance imaging is an imaging technology designed to probe anatomical architectures of biological samples in an in vivo and non-invasive manner through measuring water diffusion. The contribution of this paper is threefold. First it proposes a new method to identify and estimate multiple diffusion directions within a voxel through a new and identifiable parametrization of the widely used multi-tensor model. Unlike many existing methods, this method focuses on the estimation of diffusion directions rather than the diffusion tensors. Second, this paper proposes a novel direction smoothing method which greatly improves direction estimation in regions with crossing fibers. This smoothing method is shown to have excellent theoretical and empirical properties. Lastly, this paper develops a fiber tracking algorithm that can handle multiple directions within a voxel. The overall methodology is illustrated with simulated data and a data set collected for the study of Alzheimer's disease by the Alzheimer's Disease Neuroimaging Initiative (ADNI).

Recommendations

• Statistical diffusion tensor imaging: From data quality to fiber tracking.
• Total variation based spatial brain fiber orientation estimation
• Finsler streamline tracking with single tensor orientation distribution function for high angular resolution diffusion imaging
• Neuronal fiber-tracking via optimal mass transportation
• New algorithms for local and global fiber tractography in diffusion-weighted magnetic resonance imaging

Cited in

(9)

• DTI segmentation and fiber tracking using metrics on multivariate normal distributions
• Total variation based spatial brain fiber orientation estimation
• Network modeling in biology: statistical methods for gene and brain networks
• Discussion of ``Fiber direction estimation in diffusion MRI
• Statistical diffusion tensor imaging: From data quality to fiber tracking.
• dmri.tracking
• Finsler streamline tracking with single tensor orientation distribution function for high angular resolution diffusion imaging
• Crossing fibers detection with an analytical high order tensor decomposition
• Modeling glioma invasion with anisotropy- and hypoxia-triggered motility enhancement: from subcellular dynamics to macroscopic PDEs with multiple taxis

This page was built for publication: Fiber direction estimation, smoothing and tracking in diffusion MRI

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q125183)