First passage time of loop formation in chromatin chains

DOI10.1137/24M1719402MaRDI QIDQ6908008zbMATH OpenFDO

Authors Zhenquan Zhang, Yangchen Guo, Zihao Wang, Jiajun Zhang

Publication date 1 November 2025

Published in SIAM Journal on Applied Mathematics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1137/24M1719402

zbMATH Keywords

chromatinfirst passage timepolymer loopingstochastic processes

Mathematics Subject Classification ID

PDEs in connection with biology, chemistry and other natural sciences (35Q92) Generalized stochastic processes (60G20) Statistical mechanics of polymers (82D60) Biochemistry, molecular biology (92C40)

Cites work

• Dynamic looping of a free-draining polymer
• Kinetics of diffusing polymer encounter in confined cellular microdomains
• Mean first-passage times in confined media: from Markovian to non-Markovian processes
• Optimizing the principal eigenvalue of the Laplacian in a sphere with interior traps
• Spectra of manifolds less a small domain
• Strong Localized Perturbations of Eigenvalue Problems

Cited in

(1)

• An analytically tractable framework for transcription-extrusion coupling in chromatin loop formation

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