Floating prioritized subset analysis: A powerful method to detect differentially expressed genes

DOI10.1016/J.CSDA.2010.07.023MaRDI QIDQ452717zbMATH OpenOpenAlexFDO

Authors Wen-Chung Lee, Wan-Yu Lin

Publication date 15 September 2012

Published in Computational Statistics and Data Analysis (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.csda.2010.07.023

zbMATH Keywords

false discovery rategene expressionmicroarraymultiple comparisonsmultiple hypothesis testingsimultaneous inference

Mathematics Subject Classification ID

Paired and multiple comparisons; multiple testing (62J15) Applications of statistics to biology and medical sciences; meta analysis (62P10) Biochemistry, molecular biology (92C40) Medical applications (general) (92C50) Genetics and epigenetics (92D10)

Recommendations

• Incorporating the number of true null hypotheses to improve power in multiple testing: application to gene microarray data
• Adaptive filtering increases power to detect differentially expressed genes
• Controlling the number of false discoveries: application to high-dimensional genomic data
• Estimation procedures for the false discovery rate: a systematic comparison for microarray data
• On the identification of differentially expressed genes: Improving the generalized F-statistics for Affymetrix microarray gene expression data

Cites work

• A Bayesian False Discovery Rate for Multiple Testing
• A Direct Approach to False Discovery Rates
• Controlling the number of false discoveries: application to high-dimensional genomic data
• False discovery control with p-value weighting
• scientific article; zbMATH DE number 720689 (Why is no real title available?)
• Multiple Hypotheses Testing with Weights
• Sample size calculations for controlling the distribution of false discovery proportion in microarray experiments
• Statistical significance for genomewide studies
• Statistical Significance Threshold Criteria For Analysis of Microarray Gene Expression Data
• The Behavior of the P-Value When the Alternative Hypothesis is True

Cited in

(1)

• Adaptive filtering increases power to detect differentially expressed genes

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• fdrtool

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