Michaelis Menten equation (bi bi reaction ping pong with product 1 - Michaelis Menten model - steady state assumption)

Community: MathModDB

mathematical expression

Available identifiers

MaRDI QIDQ6674193 FDOQ6674193

Named after

Leonor Michaelis, Maud Menten

$v_{0} = \frac{V_{1} c_{S_{1}} c_{S_{2}}}{K_{S_{2}} c_{S_{1}} + K_{S_{1}} c_{S_{2}} + c_{S_{1}} c_{S_{2}} + \frac{K_{i S_{1}} K_{S_{2}}}{K_{i P_{1}}} c_{P_{1}} + \frac{K_{S_{2}}}{K_{i P_{1}}} c_{S_{1}} c_{P_{1}}}$
$K_{S_{1}}$ represents Michaelis constant
$K_{S_{2}}$ represents Michaelis constant
$K_{i P_{1}}$ represents inhibition constant
$K_{i S_{1}}$ represents inhibition constant
$V_{1}$ represents reaction rate
$c_{P_{1}}$ represents concentration
$c_{S_{1}}$ represents concentration
$c_{S_{2}}$ represents concentration
$v_{0}$ represents reaction rate

Contained entities

inhibition constant substrate 1 (bi bi reaction ping pong - Michaelis Menten model - steady state assumption)	$K_{i S_{1}} = \frac{k_{- 1}}{k_{1}}$
	$K_{i S_{1}}$ represents inhibition constant
	$k_{- 1}$ represents reaction rate constant
	$k_{1}$ represents reaction rate constant

Michaelis constant substrate 1 (bi bi reaction ping pong - Michaelis Menten model - steady state assumption)	$K_{S_{1}} = \frac{k_{4} (k_{- 1} + k_{2})}{k_{1} (k_{2} + k_{4})}$
	$K_{S_{1}}$ represents Michaelis constant
	$k_{- 1}$ represents reaction rate constant
	$k_{1}$ represents reaction rate constant
	$k_{2}$ represents reaction rate constant
	$k_{4}$ represents reaction rate constant

inhibition constant product 1 (bi bi reaction ping pong - Michaelis Menten model - steady state assumption)	$K_{i P_{1}} = \frac{k_{2}}{k_{- 2}}$
	$K_{i P_{1}}$ represents inhibition constant
	$k_{- 2}$ represents reaction rate constant
	$k_{2}$ represents reaction rate constant

Michaelis constant substrate 2 (bi bi reaction ping pong - Michaelis Menten model - steady state assumption)	$K_{S_{2}} = \frac{k_{2} (k_{- 3} + k_{4})}{k_{3} (k_{2} + k_{4})}$
	$K_{S_{2}}$ represents Michaelis constant
	$k_{- 3}$ represents reaction rate constant
	$k_{2}$ represents reaction rate constant
	$k_{3}$ represents reaction rate constant
	$k_{4}$ represents reaction rate constant

limiting reaction rate forward (bi bi reaction ping pong)	$V_{1} = \frac{k_{2} k_{4}}{k_{2} + k_{4}} c_{E_{0}}$
	$V_{1}$ represents reaction rate
	$c_{E_{0}}$ represents concentration
	$k_{2}$ represents reaction rate constant
	$k_{4}$ represents reaction rate constant

Specializations

Michaelis Menten equation (bi bi reaction ping pong without products - Michaelis Menten model - steady state assumption)

Further links

Item	Property
bi bi reaction ping pong mechanism Michaelis Menten model with product 1 (steady state assumption)	contains
Michaelis Menten equation (bi bi reaction ping pong with products 1 and 2 - Michaelis Menten model - steady state assumption)	specialized by

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