Eadie Hofstee equation (uni uni reaction without product and non-competitive complete inhibition - steady state assumption)

Community: MathModDB

deterministic expression	dimensional expression	linear equation	mathematical expression	static expression

Available identifiers

MaRDI QIDQ6674329 FDOQ6674329

Named after

George Sharpe Eadie, Barend Hendrik Jan Hofstee

$v_{0} = \frac{V_{m a x, f}}{1 + \frac{c_{I}}{K_{i u}}} - \frac{K_{m} (1 + \frac{c_{I}}{K_{i c}})}{1 + \frac{c_{I}}{K_{i u}}} \frac{v_{0}}{c_{S}}$
$K_{S}$ represents Michaelis constant substrate (uni uni reaction - steady state assumption)
$K_{i c}$ represents competitive inhibition constant (uni uni reaction reversible inhibition)
$K_{i u}$ represents uncompetitive inhibition constant (uni uni reaction reversible inhibition)
$V_{m a x, f}$ represents limiting reaction rate (uni uni reaction - forward)
$c_{I}$ represents inhibitor concentration
$c_{S}$ represents substrate concentration
$v_{0}$ represents initial reaction rate

Further links

Item	Property
linear parameter estimation (uni uni reaction without product and non-competitive complete inhibition - Eadie Hofstee model - steady state assumption)	contains
Michaelis Menten equation (uni uni reaction without product and non-competitive complete inhibition - steady state assumption)	linearized by
uni uni reaction non-competitive complete inhibition (Eadie Hofstee model without product - steady state assumption)	contains

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