Lineweaver Burk equation (uni uni reaction without product and non-competitive complete inhibition - steady state assumption)

Community: MathModDB

deterministic formula	formula	linear formula	static formula

Available identifiers

MaRDI QIDQ6674471FDOQ6674471

Named after

Hans Lineweaver, Dean Burk

$\frac{1}{v_{0}} = \frac{1 + \frac{c_{I}}{K_{i u}}}{V_{m a x, f}} + \frac{K_{m} (1 + \frac{c_{I}}{K_{i c}})}{V_{m a x, f} c_{S}}$
$K_{S}$ represents Michaelis constant substrate (uni uni reaction - steady state assumption)
$K_{i c}$ represents competitive inhibition constant (uni uni reaction reversible inhibition)
$K_{i u}$ represents uncompetitive inhibition constant (uni uni reaction reversible inhibition)
$V_{m a x, f}$ represents limiting reaction rate (uni uni reaction - forward)
$c_{I}$ represents inhibitor concentration
$c_{S}$ represents substrate concentration
$v_{0}$ represents initial reaction rate

Further links

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linear parameter estimation (uni uni reaction without product and non-competitive complete inhibition - Lineweaver Burk model - steady state assumption)	contains
Michaelis Menten equation (uni uni reaction without product and non-competitive complete inhibition - steady state assumption)	linearized by
uni uni reaction non-competitive complete inhibition (Lineweaver Burk model without product - steady state assumption)	contains

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