Michaelis Menten equation (bi bi reaction ordered with product 2 and single central complex - steady state assumption)

Community: MathModDB

deterministic expression

mathematical expression

nonlinear equation

static expression

Available identifiers

MaRDI QIDQ6674501 FDOQ6674501

Named after

Leonor Michaelis, Maud Menten

$v_0=\frac{V_{max,f}{c}_{S_1}{c}_{S_2}}{K_{i{S}_1}{K}_{S_2}+K_{S_2}{c}_{S_1}+K_{S_1}{c}_{S_2}+\frac{K_{i{S}_1}{K}_{S_2}{K}_{P_1}}{K_{i{P}_1}{K}_{P_2}}{c}_{P_2}+c_{S_1}{c}_{S_2}+\frac{K_{S_2}{K}_{P_1}}{K_{i{P}_1}{K}_{P_2}}{c}_{S_1}{c}_{P_2}+\frac{1}{K_{i{P}_2}}{c}_{S_1}{c}_{S_2}{c}_{P_2}}$

$K_{P_1}$ represents Michaelis constant

$K_{P_2}$ represents Michaelis constant

$K_{S_1}$ represents Michaelis constant substrate 1 (bi bi reaction ordered with single central complex - steady state assumption)

$K_{S_2}$ represents Michaelis constant substrate 2 (bi bi reaction ordered with single central complex - steady state assumption)

$K_{i{P}_1}$ represents inhibition constant

$K_{i{P}_2}$ represents inhibition constant

$K_{i{S}_1}$ represents inhibition constant

$V_{max,f}$ represents limiting reaction rate (bi bi reaction ordered mechanism with single central complex - forward)

$c_{P_2}$ represents product concentration

$c_{S_1}$ represents substrate concentration

$c_{S_2}$ represents substrate concentration

$v_0$ represents initial reaction rate

Contained entities

Michaelis constant product 1 (bi bi reaction ordered - single central complex - Michaelis Menten model - steady state assumption)	$K_{P_1}=\frac{k_{-1}{k}_{-2}}{k_{-5}(k_{-1}+k_{-2})}$
	$K_{P_1}$ represents Michaelis constant
	$k_{-1}$ represents reaction rate constant
	$k_{-2}$ represents reaction rate constant
	$k_{-5}$ represents reaction rate constant
inhibition constant product 2 (bi bi reaction ordered - single central complex - Michaelis Menten model - steady state assumption)	$K_{i{P}_2}=\frac{k_4+k_5}{k_{-4}}$
	$K_{i{P}_2}$ represents inhibition constant
	$k_{-4}$ represents reaction rate constant
	$k_4$ represents reaction rate constant
	$k_5$ represents reaction rate constant
Michaelis constant product 2 (bi bi reaction ordered - single central complex - Michaelis Menten model - steady state assumption)	$K_{P_2}=\frac{k_{-1}(k_{-2}+k_4)}{k_{-4}(k_{-1}+k_{-2})}$
	$K_{P_2}$ represents Michaelis constant
	$k_{-1}$ represents reaction rate constant
	$k_{-2}$ represents reaction rate constant
	$k_{-4}$ represents reaction rate constant
	$k_4$ represents reaction rate constant
inhibition constant substrate 1 (bi bi reaction ordered - single central complex - Michaelis Menten model - steady state assumption)	$K_{i{S}_1}=\frac{k_{-1}}{k_1}$
	$K_{i{S}_1}$ represents inhibition constant
	$k_{-1}$ represents reaction rate constant
	$k_1$ represents reaction rate constant
inhibition constant product 1 (bi bi reaction ordered - single central complex - Michaelis Menten model - steady state assumption)	$K_{i{P}_1}=\frac{k_5}{k_{-5}}$
	$K_{i{P}_1}$ represents inhibition constant
	$k_{-5}$ represents reaction rate constant
	$k_5$ represents reaction rate constant

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