Michaelis Menten equation (bi bi reaction ordered with products 1 and 2 and single central complex - steady state assumption)

Community: MathModDB

formula

Available identifiers

MaRDI QIDQ6674503FDOQ6674503

Named after

Leonor Michaelis, Maud Menten

$v_{0} = \frac{V_{1} V_{2} (c_{S_{1}} c_{S_{2}} - \frac{c_{P_{1}} c_{P_{2}}}{K_{e q}})}{V_{2} K_{i S_{1}} K_{S_{2}} + V_{2} K_{S_{2}} c_{S_{1}} + V_{2} K_{S_{1}} c_{S_{2}} + \frac{V_{1} K_{P_{1}}}{K_{e q}} c_{P_{2}} + \frac{V_{1} K_{P_{2}}}{K_{e q}} c_{P_{1}} + V_{2} c_{S_{1}} c_{S_{2}} + \frac{V_{1} K_{P_{1}}}{K_{i S_{1}} K_{e q}} c_{S_{1}} c_{P_{2}} + \frac{V_{1}}{K_{e q}} c_{P_{1}} c_{P_{2}} + \frac{V_{2} K_{S_{1}}}{K_{i P_{1}}} c_{S_{1}} c_{P_{1}} + \frac{V_{2}}{K_{i P_{2}}} c_{S_{1}} c_{S_{2}} c_{P_{2}} + \frac{V_{1}}{K_{i S_{2}} K_{e q}} c_{S_{2}} c_{P_{1}} c_{P_{2}}}$
$K_{P_{1}}$ represents Michaelis constant
$K_{P_{2}}$ represents Michaelis constant
$K_{S_{1}}$ represents Michaelis constant substrate 1 (bi bi reaction ordered with single central complex - steady state assumption)
$K_{S_{2}}$ represents Michaelis constant substrate 2 (bi bi reaction ordered with single central complex - steady state assumption)
$K_{e q}$ represents equilibrium constant
$K_{i P_{1}}$ represents inhibition constant
$K_{i P_{2}}$ represents inhibition constant
$K_{i S_{1}}$ represents inhibition constant
$K_{i S_{2}}$ represents inhibition constant
$V_{1}$ represents limiting reaction rate (bi bi reaction ordered mechanism with single central complex - forward)
$V_{2}$ represents limiting reaction rate backward (bi bi reaction ordered - single central complex)
$c_{P_{1}}$ represents concentration
$c_{P_{2}}$ represents concentration
$c_{S_{1}}$ represents concentration
$c_{S_{2}}$ represents concentration
$v_{0}$ represents reaction rate

Contained entities

Further links

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bi bi reaction ordered mechanism Michaelis Menten model with products 1 and 2 and single central complex (steady state assumption)	contains

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