Michaelis Menten equation (bi bi reaction ordered with products 1 and 2 and single central complex - steady state assumption)

Community: MathModDB

mathematical expression

Available identifiers

MaRDI QIDQ6674503

equation for bi bi reaction with ordered mechanism and products 1 and 2 and Single Central Complex following steady state assumption, named after Leonor Michaelis, Maud Menten

Defining Formula: $v_{0} = \frac{V_{1} V_{2} (c_{S_{1}} c_{S_{2}} - \frac{c_{P_{1}} c_{P_{2}}}{K_{e q}})}{V_{2} K_{i S_{1}} K_{S_{2}} + V_{2} K_{S_{2}} c_{S_{1}} + V_{2} K_{S_{1}} c_{S_{2}} + \frac{V_{1} K_{P_{1}}}{K_{e q}} c_{P_{2}} + \frac{V_{1} K_{P_{2}}}{K_{e q}} c_{P_{1}} + V_{2} c_{S_{1}} c_{S_{2}} + \frac{V_{1} K_{P_{1}}}{K_{i S_{1}} K_{e q}} c_{S_{1}} c_{P_{2}} + \frac{V_{1}}{K_{e q}} c_{P_{1}} c_{P_{2}} + \frac{V_{2} K_{S_{1}}}{K_{i P_{1}}} c_{S_{1}} c_{P_{1}} + \frac{V_{2}}{K_{i P_{2}}} c_{S_{1}} c_{S_{2}} c_{P_{2}} + \frac{V_{1}}{K_{i S_{2}} K_{e q}} c_{S_{2}} c_{P_{1}} c_{P_{2}}}$
$K_{P_{1}}$ represents Michaelis constant
$K_{P_{2}}$ represents Michaelis constant
$K_{S_{1}}$ represents Michaelis constant substrate 1 (bi bi reaction ordered with single central complex - steady state assumption)
$K_{S_{2}}$ represents Michaelis constant substrate 2 (bi bi reaction ordered with single central complex - steady state assumption)
$K_{e q}$ represents equilibrium constant
$K_{i P_{1}}$ represents inhibition constant
$K_{i P_{2}}$ represents inhibition constant
$K_{i S_{1}}$ represents inhibition constant
$K_{i S_{2}}$ represents inhibition constant
$V_{1}$ represents limiting reaction rate (bi bi reaction ordered mechanism with single central complex - forward)
$V_{2}$ represents limiting reaction rate backward (bi bi reaction ordered - single central complex)
$c_{P_{1}}$ represents concentration
$c_{P_{2}}$ represents concentration
$c_{S_{1}}$ represents concentration
$c_{S_{2}}$ represents concentration
$v_{0}$ represents reaction rate

List of contained entities

Michaelis constant product 1 (bi bi reaction ordered - single central complex - Michaelis Menten model - steady state assumption)	$K_{P_{1}} = \frac{k_{- 1} k_{- 2}}{k_{- 5} (k_{- 1} + k_{- 2})}$
	$K_{P_{1}}$ represents Michaelis constant
	$k_{- 1}$ represents reaction rate constant
	$k_{- 2}$ represents reaction rate constant
	$k_{- 5}$ represents reaction rate constant

Michaelis constant product 2 (bi bi reaction ordered - single central complex - Michaelis Menten model - steady state assumption)	$K_{P_{2}} = \frac{k_{- 1} (k_{- 2} + k_{4})}{k_{- 4} (k_{- 1} + k_{- 2})}$
	$K_{P_{2}}$ represents Michaelis constant
	$k_{- 1}$ represents reaction rate constant
	$k_{- 2}$ represents reaction rate constant
	$k_{- 4}$ represents reaction rate constant
	$k_{4}$ represents reaction rate constant

equilibrium constant (bi bi reaction ordered - single central complex - Michaelis Menten model - steady state assumption)	$K_{e q} = \frac{k_{1} k_{2} k_{4} k_{5}}{k_{- 1} k_{- 2} k_{- 4} k_{- 5}}$
	$K_{e q}$ represents equilibrium constant
	$k_{- 1}$ represents reaction rate constant
	$k_{- 2}$ represents reaction rate constant
	$k_{- 4}$ represents reaction rate constant
	$k_{- 5}$ represents reaction rate constant
	$k_{1}$ represents reaction rate constant
	$k_{2}$ represents reaction rate constant
	$k_{4}$ represents reaction rate constant
	$k_{5}$ represents reaction rate constant

inhibition constant product 1 (bi bi reaction ordered - single central complex - Michaelis Menten model - steady state assumption)	$K_{i P_{1}} = \frac{k_{5}}{k_{- 5}}$
	$K_{i P_{1}}$ represents inhibition constant
	$k_{- 5}$ represents reaction rate constant
	$k_{5}$ represents reaction rate constant

inhibition constant product 2 (bi bi reaction ordered - single central complex - Michaelis Menten model - steady state assumption)	$K_{i P_{2}} = \frac{k_{4} + k_{5}}{k_{- 4}}$
	$K_{i P_{2}}$ represents inhibition constant
	$k_{- 4}$ represents reaction rate constant
	$k_{4}$ represents reaction rate constant
	$k_{5}$ represents reaction rate constant

inhibition constant substrate 1 (bi bi reaction ordered - single central complex - Michaelis Menten model - steady state assumption)	$K_{i S_{1}} = \frac{k_{- 1}}{k_{1}}$
	$K_{i S_{1}}$ represents inhibition constant
	$k_{- 1}$ represents reaction rate constant
	$k_{1}$ represents reaction rate constant

inhibition constant substrate 2 (bi bi reaction ordered - single central complex - Michaelis Menten model - steady state assumption)	$K_{i S_{2}} = \frac{k_{- 1} + k_{- 2}}{k_{2}}$
	$K_{i S_{2}}$ represents inhibition constant
	$k_{- 1}$ represents reaction rate constant
	$k_{- 2}$ represents reaction rate constant
	$k_{2}$ represents reaction rate constant

Further items linking to Michaelis Menten equation (bi bi reaction ordered with products 1 and 2 and single central complex - steady state assumption)

Item	Property
bi bi reaction ordered mechanism Michaelis Menten model with products 1 and 2 and single central complex (steady state assumption)	contains

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