Michaelis Menten equation (bi bi reaction Theorell-Chance with products 1 and 2 - Michaelis Menten model - steady state assumption)

Community: MathModDB

mathematical expression

Available identifiers

MaRDI QIDQ6674508 FDOQ6674508

Named after

Hugo Theorell, Leonor Michaelis, Maud Menten

$v_0=\frac{V_1{V}_2(c_{S_1}{c}_{S_2}-\frac{c_{P_1}{c}_{P_2}}{K_{eq}})}{V_2{K}_{i{S}_1}{K}_{S_2}+V_2{K}_{S_2}{c}_{S_1}+V_2{K}_{S_1}{c}_{S_2}+\frac{V_1{K}_{P_2}}{K_{eq}}{c}_{P_1}+\frac{V_1{K}_{P_1}}{K_{eq}}{c}_{P_2}+V_2{c}_{S_1}{c}_{S_2}+\frac{V_1{K}_{P_2}}{K_{i{S}_1}{K}_{eq}}{c}_{S_1}{c}_{P_1}+\frac{V_2{K}_{S_1}}{K_{i{P}_2}}{c}_{S_2}{c}_{P_2}+\frac{V_1}{K_{eq}}{c}_{P_1}{c}_{P_2}}$

$K_{P_1}$ represents Michaelis constant

$K_{P_2}$ represents Michaelis constant

$K_{S_1}$ represents Michaelis constant

$K_{S_2}$ represents Michaelis constant

$K_{eq}$ represents equilibrium constant

$K_{i{P}_2}$ represents inhibition constant

$K_{i{S}_1}$ represents inhibition constant

$V_1$ represents reaction rate

$V_2$ represents reaction rate

$c_{P_1}$ represents concentration

$c_{P_2}$ represents concentration

$c_{S_1}$ represents concentration

$c_{S_2}$ represents concentration

$v_0$ represents reaction rate

Contained entities

Michaelis constant product 1 (bi bi reaction Theorell-Chance - Michaelis Menten model - steady state assumption)	$K_{P_1}=\frac{k_{-1}}{k_{-2}}$
	$K_{P_1}$ represents Michaelis constant
	$k_{-1}$ represents reaction rate constant
	$k_{-2}$ represents reaction rate constant
limiting reaction rate backward (bi bi reaction Theorell-Chance)	$V_2=k_{-1}{c}_{E_0}$
	$V_2$ represents reaction rate
	$c_{E_0}$ represents concentration
	$k_{-1}$ represents reaction rate constant
Michaelis constant product 2 (bi bi reaction Theorell-Chance - Michaelis Menten model - steady state assumption)	$K_{P_2}=\frac{k_{-1}}{k_{-3}}$
	$K_{P_2}$ represents Michaelis constant
	$k_{-1}$ represents reaction rate constant
	$k_{-3}$ represents reaction rate constant
equilibrium constant (bi bi reaction Theorell-Chance - Michaelis Menten model - steady state assumption)	$K_{eq}=\frac{k_1{k}_2{k}_3}{k_{-1}{k}_{-2}{k}_{-3}}$
	$K_{eq}$ represents equilibrium constant
	$k_{-1}$ represents reaction rate constant
	$k_{-2}$ represents reaction rate constant
	$k_{-3}$ represents reaction rate constant
	$k_1$ represents reaction rate constant
	$k_2$ represents reaction rate constant
	$k_3$ represents reaction rate constant
inhibition constant substrate 1 (bi bi reaction Theorell-Chance - Michaelis Menten model - steady state assumption)	$K_{i{S}_1}=\frac{k_{-1}}{k_1}$
	$K_{i{S}_1}$ represents inhibition constant
	$k_{-1}$ represents reaction rate constant
	$k_1$ represents reaction rate constant
inhibition constant product 2 (bi bi reaction Theorell-Chance - Michaelis Menten model - steady state assumption)	$K_{i{P}_2}=\frac{k_3}{k_{-3}}$
	$K_{i{P}_2}$ represents inhibition constant
	$k_{-3}$ represents reaction rate constant
	$k_3$ represents reaction rate constant
Michaelis constant substrate 2 (bi bi reaction Theorell-Chance - Michaelis Menten model - steady state assumption)	$K_{S_2}=\frac{k_3}{k_2}$
	$K_{S_2}$ represents Michaelis constant
	$k_2$ represents reaction rate constant
	$k_3$ represents reaction rate constant
Michaelis constant substrate 1 (bi bi reaction Theorell-Chance - Michaelis Menten model - steady state assumption)	$K_{S_1}=\frac{k_3}{k_1}$
	$K_{S_1}$ represents Michaelis constant
	$k_1$ represents reaction rate constant
	$k_3$ represents reaction rate constant
limiting reaction rate forward (bi bi reaction Theorell-Chance)	$V_1=k_3{c}_{E_0}$
	$V_1$ represents reaction rate
	$c_{E_0}$ represents concentration
	$k_3$ represents reaction rate constant

Further links

Item	Property
bi bi reaction Theorell-Chance mechanism Michaelis Menten model with products 1 and 2 (steady state assumption)	contains

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