GENIUS-MAWII: for robust Mendelian randomization with many weak invalid instruments

DOI10.1093/JRSSSB/QKAE024MaRDI QIDQ6670546zbMATH OpenFDO

Authors Ting Ye, Zhong-Hua Liu, Baoluo Sun, Eric J. Tchetgen Tchetgen

Publication date 23 January 2025

Published in Journal of the Royal Statistical Society. Series B. Statistical Methodology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1093/JRSSSB/QKAE024

zbMATH Keywords

causal inferenceexclusion restrictionheteroscedastic errorsinstrumental variablesmany weak momentspleiotropy

Mathematics Subject Classification ID

Statistics (62-XX)

Cited in

(3)

• Mendelian randomization methods for causal inference: estimands, identification and inference
• A focusing framework for testing bi-directional causal effects in Mendelian randomization
• A modified debiased inverse-variance weighted estimator in two-sample summary-data Mendelian randomization

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