Generalized Connectivity Matrix Response Regression with Applications in Brain Connectivity Studies

DOI10.1080/10618600.2022.2074434MaRDI QIDQ6093505zbMATH OpenFDO

Authors Jingfei Zhang, Wei Sun, Lexin Li

Publication date 9 October 2023

Published in Journal of Computational and Graphical Statistics (Search for Journal in Brave)

Full work available at URL https://arxiv.org/abs/1810.03192

zbMATH Keywords

computational and statistical errorsgeneralized linear modelhigh-dimensional regressionneuroimagingtensors

Mathematics Subject Classification ID

Statistics (62-XX)

Abstract: Multiple-subject network data are fast emerging in recent years, where a separate connectivity matrix is measured over a common set of nodes for each individual subject, along with subject covariates information. In this article, we propose a new generalized matrix response regression model, where the observed networks are treated as matrix-valued responses and the subject covariates as predictors. The new model characterizes the population-level connectivity pattern through a low-rank intercept matrix, and the effect of subject covariates through a sparse slope tensor. We develop an efficient alternating gradient descent algorithm for parameter estimation, and establish the non-asymptotic error bound for the actual estimator from the algorithm, which quantifies the interplay between the computational and statistical errors. We further show the strong consistency for graph community recovery, as well as the edge selection consistency. We demonstrate the efficacy of our method through simulations and two brain connectivity studies.

Cited in

(11)

• Dynamic GSCANO (generalized structured canonical correlation analysis) with applications to the analysis of effective connectivity in functional neuroimaging data
• A Generalized Multivariate Autoregressive (GmAR)-Based Approach for EEG Source Connectivity Analysis
• Matrix Graph Hypothesis Testing and Application in Brain Connectivity Alternation Detection
• Brain connectivity alteration detection via matrix‐variate differential network model
• Hypothesis Testing of Matrix Graph Model with Application to Brain Connectivity Analysis
• Learning brain connectivity in social cognition with dynamic network regression
• Multiplex Depth for Network-Valued Data and Applications
• Network-Based Neighborhood Regression
• Statistical inference on high-dimensional covariate-dependent Gaussian graphical regressions
• High-Dimensional Covariance Regression with Application to Co-Expression QTL Detection
• Low-Rank Contextual Reinforcement Learning from Heterogeneous Human Feedback

This page was built for publication: Generalized Connectivity Matrix Response Regression with Applications in Brain Connectivity Studies

Report a bug (only for logged in users!)Click here to report a bug for this page (MaRDI item Q6093505)