Hypothesis Testing Under Mixture Models: Application to Genetic Linkage Analysis

DOI10.1111/J.0006-341X.1999.00065.XMaRDI QIDQ4666521zbMATH OpenOpenAlexWikidataFDO

Authors Paul J. Rathouz, Kung-Yee Liang

Publication date 13 April 2005

Published in Biometrics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1111/j.0006-341x.1999.00065.x

zbMATH Keywords

likelihood ratio statisticsscore functionchi-squared distributiongenetic linkage analysis

Mathematics Subject Classification ID

Parametric hypothesis testing (62F03) Applications of statistics to biology and medical sciences; meta analysis (62P10) Asymptotic distribution theory in statistics (62E20) Genetics and epigenetics (92D10) Testing in survival analysis and censored data (62N03)

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Cites work

• Linear Statistical Inference and its Applications

Cited in

(25)

• Group sequential testing of homogeneity in genetic linkage analysis
• Adjusting for Population Heterogeneity and Misspecified Haplotype Frequencies When Testing Nonparametric Null Hypotheses in Statistical Genetics
• Homogeneity test in distribution mixtures and application to major genes detection
• A new approach of statistical hypothesis verification
• A class of pseudolikelihood ratio tests for homogeneity in exponential tilt mixture models
• Mixture of the Riesz distribution with respect to a multivariate Poisson
• A moment-based test of genetic linkage under heterogeneity
• Likelihood ratio testing for admixture models with application to genetic linkage analysis
• Parametric Estimation in a Genetic Mixture Model with Application to Nuclear Family Data
• SUPPLEMENTARY SCORE TEST IN MIXTURE MODEL
• Mixture cure model with an application to interval mapping of quantitative trait loci
• A moment-based test for the homogeneity in mixture natural exponential family with quadratic variance functions
• Efficient testing and effect size estimation for set‐based genetic association inference via semiparametric multilevel mixture modeling
• Local score tests in mixture exponential family
• Hypothesis testing in a mixture case-control model
• Local likelihood ratio tests in the normal mixture model
• Statistical analysis in genetic studies of mental illnesses
• Hereditarity of potential matrices and positive affine prediction of nonnegative risks from mixture models
• scientific article; zbMATH DE number 2204562 (Why is no real title available?)
• Empirical likelihood-based inference for genetic mixture models
• The admixture model in linkage analysis
• Statistical inference on mixing proportion
• Testing for homogeneity in genetic linkage analysis
• A moment-based test for the mixture distributions with small sample sizes and its application
• scientific article; zbMATH DE number 5943327 (Why is no real title available?)

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