Integrative Structurally Detailed Model of Calcium Dynamics in the Cardiac Diad

DOI10.1137/05064549XMaRDI QIDQ5432417zbMATH OpenOpenAlexFDO

Authors Antti Juho Tanskanen, Raimond L. Winslow

Publication date 3 January 2008

Published in Multiscale Modeling & Simulation (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1137/05064549x

zbMATH Keywords

calcium-induced calcium releasecardiac myocyteFokker-Planck equationLaplace equation

Mathematics Subject Classification ID

Reaction-diffusion equations (35K57) PDEs in connection with biology, chemistry and other natural sciences (35Q92) Biophysics (92C05) Physiology (general) (92C30)

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• Dynamics of adrenergic signaling in cardiac myocytes and implications for pharmacological treatment
• Linkages of calcium-induced calcium release in a cardiomyocyte simulated by a system of seven coupled partial differential equations
• The dynamics of Ca\(^{2+}\) within the sarcoplasmic reticulum of frog skeletal muscle. A simulation study
• Calcium dynamics in cardiac excitatory and non-excitatory cells and the role of gap junction
• \(\mathrm{IP}_3\mathrm{R}\) activity increases propensity of RyR-mediated sparks by elevating dyadic \([\mathrm{Ca}^{2+}]\)
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• Computational modelling of the initiation and development of spontaneous intracellular \(Ca^{2+}\) waves in ventricular myocytes
• Effect of Source Geometry on Interdependent Calcium and Inositol 1; 4; 5-Trisphosphate Dynamics in a Cardiac Myocyte Cell
• An integrated formulation of anisotropic force-calcium relations driving spatio-temporal contractions of cardiac myocytes
• DYNAMICS OF CARDIAC INTRACELLULARCa²⁺HANDLING — FROM EXPERIMENTS TO VIRTUAL CELLS
• Multiscale modeling and numerical simulation of calcium cycling in cardiac myocytes
• The functional role of cardiac T-tubules explored in a model of rat ventricular myocytes
• Effectiveness of numerical techniques for calculating the quantity of Ca²⁺species during calcium sparks in heart muscle
• Model of calcium-induced calcium release mechanism in cardiac cells
• The effect of heterogeneously-distributed RyR channels on calcium dynamics in cardiac myocytes
• Models of cardiac excitation-contraction coupling in ventricular myocytes

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