Interim Analyses in 2 x 2 Crossover Trials

DOI10.2307/2532994MaRDI QIDQ4335720zbMATH OpenOpenAlexWikidataFDO

Authors Richard J. Cook

Publication date 11 August 1997

Published in Biometrics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.2307/2532994

zbMATH Keywords

chemotherapyinterim analyseslong term crossover trialspowersample size calculationssimultaneous patient entrytreatment effectstwo-stage sequential designtype I error rate

Mathematics Subject Classification ID

Sequential statistical design (62L05) Sequential statistical analysis (62L10) Applications of statistics to biology and medical sciences; meta analysis (62P10)

Recommendations

• Use of Two-Stage Test Statistic in the Two-Period Crossover Trials
• The performance of a two-stage analysis of ABAB/BABA crossover trials
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Cited in

(11)

• The performance of a two-stage analysis of ABAB/BABA crossover trials
• The finite sample performance of the two-stage analysis of a two-period crossover trial
• Using the Maximum Test Statistic in the Two-Period Crossover Clinical Trial
• Minimal balanced repeated measurements designs
• scientific article; zbMATH DE number 4044985 (Why is no real title available?)
• A note on the sample size determination in two-period repeated measurements crossover design with application to clinical trials
• Use of Two-Stage Test Statistic in the Two-Period Crossover Trials
• Construction of repeated measurements designs strongly balanced for residual effects
• Notes on power comparison between the sequential parallel comparison and other commonly-used designs
• Interim analysis incorporating short- and long-term binary endpoints
• Fixed-width confidence interval of log odds ratio in correlated setup for crossover design

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