Intracellular protein dynamics as a mathematical problem

DOI10.3934/DCDSB.2016060MaRDI QIDQ325773zbMATH OpenOpenAlexFDO

Authors Mirosław Lachowicz, Martin Parisot, Zuzanna Szymańska

Publication date 11 October 2016

Published in Discrete and Continuous Dynamical Systems. Series B (Search for Journal in Brave)

Full work available at URL https://doi.org/10.3934/dcdsb.2016060

zbMATH Keywords

existenceintracellular dynamicmicrotubulesparabolic hyperbolic coupled modeluniqueness

Mathematics Subject Classification ID

Existence problems for PDEs: global existence, local existence, non-existence (35A01) Reaction-diffusion equations (35K57) Initial-boundary value problems for PDEs of mixed type (35M13) PDEs in connection with biology, chemistry and other natural sciences (35Q92) General biology and biomathematics (92B05) Cell biology (92C37)

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Cites work

• A spatial model of cellular molecular trafficking including active transport along microtubules
• Dissecting the dynamics of the Hes1 genetic oscillator
• Hopf bifurcation in a gene regulatory network model: molecular movement causes oscillations
• Influence of the nuclear membrane, active transport, and cell shape on the Hes1 and p53-Mdm2 pathways: insights from spatio-temporal modelling
• Mathematical analysis of a modular network coordinating the cell cycle and apoptosis
• Mathematical modeling of the intracellular protein dynamics: the importance of active transport along microtubules
• Spatial aspects in the SMAD signaling pathway
• Spatio-temporal modelling of the Hes1 and p53-Mdm2 intracellular signalling pathways
• Well-posedness of a linear spatio-temporal model of the JAK2/STAT5 signaling pathway

Cited in

(11)

• Mathematical analysis of models for reaction kinetics in intracellular environments
• Computational modelling of cancer development and growth: modelling at multiple scales and multiscale modelling
• A spatial model of cellular molecular trafficking including active transport along microtubules
• Binding protein-dependent transporters: An answer of mathematics to biology
• Internal degrees of freedom in a thermodynamical model for intracell biological transport
• Justification of quasi-stationary approximation in models of gene expression of a self-regulating protein
• Mathematical modeling of the intracellular protein dynamics: the importance of active transport along microtubules
• The kinetics of vitamin D₃ in the osteoblastic cell
• A distributed model of intracellular mobility and its projection-difference approximation
• Multisolitons-like patterns in a one-dimensional MARCKS protein cyclic model
• Mathematical modelling of protein secretion across the endoplasmic reticulum

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