invitroTKstats
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InvitroTKstats
Description
A set of tools for processing and analyzing in vitro toxicokinetic measurements in a standardized and reproducible pipeline. The package was developed to perform frequentist and Bayesian estimation on a variety of in vitro toxicokinetic measurements including – but not limited to – chemical fraction unbound in the presence of plasma (f_up), intrinsic hepatic clearance (Clint, uL/min/million hepatocytes), and membrane permeability for oral absorption (Caco2). The methods provided by the package were described in Wambaugh et al. (2019) <doi:10.1093/toxsci/kfz205>.
This page was built for software: invitroTKstats
