o2plsda (Q100581)
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Multiomics Data Integration
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | No label defined |
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| English | o2plsda |
Multiomics Data Integration |
Statements
Junguk Hur
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Eva Feldman
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1 December 2025
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Provides functions to do 'O2PLS-DA' analysis for multiple omics data integration. The algorithm came from "O2-PLS, a two-block (X±Y) latent variable regression (LVR) method with an integral OSC filter" which published by Johan Trygg and Svante Wold at 2003 <doi:10.1002/cem.775>. 'O2PLS' is a bidirectional multivariate regression method that aims to separate the covariance between two data sets (it was recently extended to multiple data sets) (Löfstedt and Trygg, 2011 <doi:10.1002/cem.1388>; Löfstedt et al., 2012 <doi:10.1016/j.aca.2013.06.026>) from the systematic sources of variance being specific for each data set separately.
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