squant (Q115789)
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Subgroup Identification Based on Quantitative Objectives
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | No label defined |
||
| English | squant |
Subgroup Identification Based on Quantitative Objectives |
Statements
Ling Cheng
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A.s. Hedayat
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LING CHENG
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A.S. HEDAYAT
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19 August 2024
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A subgroup identification method for precision medicine based on quantitative objectives. This method can handle continuous, binary and survival endpoint for both prognostic and predictive case. For the predictive case, the method aims at identifying a subgroup for which treatment is better than control by at least a pre-specified or auto-selected constant. For the prognostic case, the method aims at identifying a subgroup that is at least better than a pre-specified/auto-selected constant. The derived signature is a linear combination of predictors, and the selected subgroup are subjects with the signature > 0. The false discover rate when no true subgroup exists is controlled at a user-specified level.
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