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1989
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incomplete data
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EM algorithm
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maximum-likelihood estimates
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numerical stability
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human pedigree analysis
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numerical examples
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genetic modelling
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racial admixture
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linkage homogeneity
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segregation analysis
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Mendelian latent trait model for schizophrenia
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heterozygote detection assay for Ataxia-telangiectasia
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quasi-Newton method of optimization
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