Group Sequential Tests for Bivariate Response: Interim Analyses of Clinical Trials with Both Efficacy and Safety Endpoints (Q4274354)

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scientific article; zbMATH DE number 481970
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Group Sequential Tests for Bivariate Response: Interim Analyses of Clinical Trials with Both Efficacy and Safety Endpoints
scientific article; zbMATH DE number 481970

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    Group Sequential Tests for Bivariate Response: Interim Analyses of Clinical Trials with Both Efficacy and Safety Endpoints (English)
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    6 January 1994
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    group sequential tests
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    bivariate response
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    bivariate testing problem
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    Type I error conditions
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    specified power
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    bivariate normal observations
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    numerical integration
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    correlated responses
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    clinical trial
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    interim analyses
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    repeated confidence intervals
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    safety endpoints
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    stopping boundaries
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