SpaTopic (Q5977855)
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Topic Inference to Identify Tissue Architecture in Multiplexed Images
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | No label defined |
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| English | SpaTopic |
Topic Inference to Identify Tissue Architecture in Multiplexed Images |
Statements
A novel spatial topic model to integrate both cell type and spatial information to identify the complex spatial tissue architecture on multiplexed tissue images without human intervention. The Package implements a collapsed Gibbs sampling algorithm for inference. The method is highly scalable to large-scale image datasets without extracting neighborhood information for every single cell. The package supports spatially resolved cell-level data analysis, topic inference, visualization, and downstream biological interpretation of tissue microenvironments.
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29 May 2026
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Nikki Xiao
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