trialdiff (Q7369570)

A transparent, rule-based framework for detecting changes between successive data cuts of clinical trial datasets, classifying those changes into clinically meaningful categories, tracing user-defined data lineage, and assessing which downstream analyses and outputs may be affected. The package is designed to complement existing low-level data frame comparison tools by adding clinical-trial-specific classification, lineage and impact-assessment layers on top of deterministic comparison. The rule-based classification is similar in spirit to the data validation infrastructure of van der Loo and de Jonge (2021) <doi:10.18637/jss.v097.i10>.