PheValuator (Q7401917)

Evaluates phenotype algorithms by developing a diagnostic prediction model using a set of noisy positives and noisy negatives. It can then apply the model to a large cohort to create a set of subjects each with a predicted probability for the health outcome of interest. This cohort can then be used to evaluate phenotype algorithms through the calculation of the necessary performance characteristics - sensitivity, specificity, and positive and negative predictive value. Based on work by Swerdel (2022) <doi:10.1016/j.jbi.2022.104177> and Swerdel (2019) <doi:10.1016/j.jbi.2019.103258>.