uncertR (Q7414869)
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Bootstrap Prediction Uncertainty and Its Biological Drivers in Gene-Expression Models
| Language | Label | Description | Also known as |
|---|---|---|---|
| default for all languages | No label defined |
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| English | uncertR |
Bootstrap Prediction Uncertainty and Its Biological Drivers in Gene-Expression Models |
Statements
Fits bootstrap ensembles of penalized regression models on bulk gene-expression data, derives per-sample uncertainty scores from out-of-bag predictions, and tests whether technical covariates explain that uncertainty. The bootstrap method is described by Efron and Tibshirani (1993, ISBN:9780412042317), and elastic-net regression follows Friedman, Hastie, and Tibshirani (2010) <doi:10.18637/jss.v033.i01>. The optional immunedeconv package, used for immune-cell deconvolution, is available from GitHub <https://github.com/omnideconv/immunedeconv>.
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3 November 2026
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