nlmixr2extra (Q74524)
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Nonlinear Mixed Effects Models in Population PK/PD, Extra Support Functions
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| English | nlmixr2extra |
Nonlinear Mixed Effects Models in Population PK/PD, Extra Support Functions |
Statements
31 January 2024
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Fit and compare nonlinear mixed-effects models in differential equations with flexible dosing information commonly seen in pharmacokinetics and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 <doi:10.1007/s10928-015-9409-1>). Differential equation solving is by compiled C code provided in the 'rxode2' package (Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>). This package is for support functions like preconditioned fits <doi:10.1208/s12248-016-9866-5>, boostrap and stepwise covariate selection.
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