Simultaneous modelling of a nonlinear multiresponse pharmacokinetic system (Q911499)

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scientific article; zbMATH DE number 4141851
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    Simultaneous modelling of a nonlinear multiresponse pharmacokinetic system
    scientific article; zbMATH DE number 4141851

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      Simultaneous modelling of a nonlinear multiresponse pharmacokinetic system (English)
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      1989
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      parameter estimation
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      Concentration-time curves
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      anticancer drug
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      metabolites
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      enzymatic pathways
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      enzymatic nonlinear model
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      multivariate measurement error
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      multinormal distribution
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      variance model
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      maximum likelihood principle
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      pharmacokinetic model
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      residual analysis
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      intrakinetic and interkinetic variabilities
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