Kinetics and mechanisms of surface-dependent coagulation factor XII activation

DOI10.1016/J.JTBI.2015.07.001MaRDI QIDQ739354zbMATH OpenOpenAlexWikidataFDO

Authors Vladislava A. Terentyeva, Anastasia N. Sveshnikova, M. Panteleev

Publication date 18 August 2016

Published in Journal of Theoretical Biology (Search for Journal in Brave)

Full work available at URL https://doi.org/10.1016/j.jtbi.2015.07.001

zbMATH Keywords

blood coagulationcontact activationdextran sulfatefactor XIIintrinsic pathway

Mathematics Subject Classification ID

Physiological flow (92C35) Kinetics in biochemical problems (pharmacokinetics, enzyme kinetics, etc.) (92C45)

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(4)

• Activation of contact pathway of blood coagulation on the lipopolysaccharide aggregates
• Mathematical model for the central reaction of protein C in blood coagulation cascade
• Kinetics and regulation of coagulation factor X activation by intrinsic tenase on phospholipid membranes
• Kinetic analysis of prothrombinase assembly and substrate delivery mechanisms

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