LSJM

MaRDI QIDQ7370861CRANFDO

Authors Léonie Courcoul, Antoine Barbieri, Hélène Jacqmin-Gadda

Last update 14 September 2026

Copyright license GNU General Public License, version 2.0, GNU General Public License, version 3.0

Software version identifier 0.1.0, PACKAGES.rds, 0.1.1

Description

Estimation of mixed models including a subject-specific variance that can be time- and covariate-dependent or defined for within- and between-visit variability. In the joint modeling framework, the package handles left truncation, interval censoring, and multistate models, and allows a flexible dependence structure between competing events and the longitudinal marker. Estimation is performed in a frequentist framework using the Marquardt-Levenberg algorithm. Methods are described in Courcoul et al. (2025) <doi:10.1002/sim.70244> and in Courcoul et al. (2026) <doi:10.1002/bimj.70123>.

Cites work

• A location-scale joint model for studying the link between the time-dependent subject-specific variability of blood pressure and competing events
• Joint model for interval-censored semicompeting events and longitudinal data with subject-specific within- and between-visits variabilities

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