Large Sample Tests for Binary Outcomes in Fixed-Dose Combination Drug Studies

DOI10.2307/2533953MaRDI QIDQ4349962zbMATH OpenOpenAlexWikidataFDO

Authors Sue-Jane Wang, H. M. James Hung

Publication date 5 January 1998

Published in Biometrics (Search for Journal in Brave)

Full work available at URL https://doi.org/10.2307/2533953

zbMATH Keywords

clinical trialmin testmonte Carlo simulationpowersignificance level

Mathematics Subject Classification ID

Parametric hypothesis testing (62F03) Applications of statistics to biology and medical sciences; meta analysis (62P10)

Recommendations

• Testing for the Existence of a Desirable Dose Combination
• VALIDITY AND APPLICABILITY OF TESTS FOR ORDERED ALTERNATIVES WITH BINARY RESPONSE FOR A CLINICAL DOSE-RESPONSE STUDY
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Cited in

(5)

• Application of Anbar's approach to hypothesis testing to detect the difference between two proportions
• TEST FOR TREATMENT EFFECT BASED ON BINARY DATA WITH RANDOM SAMPLE SIZES
• On improving the min test for the analysis of combination drug trials
• Testing for the Existence of a Desirable Dose Combination
• Large sample properties of two tests for independent joint action of two drugs

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