markerpen

Authors Yixuan Qiu, Jiebiao Wang, Jing Lei, Kathryn Roeder

Last update 14 December 2025

Copyright license GNU General Public License, version 2.0, GNU General Public License, version 3.0

Software version identifier 0.1.1, PACKAGES.rds, 0.1.0, 0.1.2

Description

Implementation of the 'MarkerPen' algorithm, short for marker gene detection via penalized principal component analysis, described in the paper by Qiu, Wang, Lei, and Roeder (2021, <doi:10.1093/bioinformatics/btab257>). 'MarkerPen' is a semi-supervised algorithm for detecting marker genes by combining prior marker information with bulk transcriptome data.

Cites work

Identification of cell-type-specific marker genes from co-expression patterns in tissue samples

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