Mechanistic Modeling of Longitudinal Shape Changes: Equations of Motion and Inverse Problems
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Abstract: This paper examines a longitudinal shape evolution model in which a 3D volume progresses through a family of elastic equilibria in response to the time-derivative of an internal force, or yank, with an additional regularization to ensure diffeomorphic transformations. We consider two different models of yank and address the long time existence and uniqueness of solutions for the equations of motion in both models. In addition, we derive sufficient conditions for the existence of an optimal yank that best describes the change from an observed initial volume to an observed volume at a later time. The main motivation for this work is the understanding of processes such as growth and atrophy in anatomical structures, where the yank could be roughly interpreted as a metabolic event triggering morphological changes. We provide preliminary results on simple examples to illustrate, under this model, the retrievability of some attributes of such events.
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Cited in
(6)- Existence and continuity of minimizers for the estimation of growth mapped evolutions for current data term and counterexamples for varifold data term
- Diffeomorphic shape evolution coupled with a reaction-diffusion PDE on a growth potential
- An operator-splitting approach for variational optimal control formulations for diffeomorphic shape matching
- Shape spaces: from geometry to biological plausibility
- Organ registration from partial surface data in augmented surgery from an optimal control perspective
- Classification of deformable smooth shapes through geodesic flows of diffeomorphisms
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