Mendelian randomization. Methods for causal inference using genetic variants

DOI10.1201/9780429324352MaRDI QIDQ5147685zbMATH OpenOpenAlexFDO

Authors Stephen Burgess, Simon G. Thompson

Publication date 27 January 2021

Full work available at URL https://doi.org/10.1201/9780429324352

zbMATH Keywords

causal inference

Mathematics Subject Classification ID

Bayesian inference (62F15) Applications of statistics to biology and medical sciences; meta analysis (62P10) Genetics and epigenetics (92D10) Research exposition (monographs, survey articles) pertaining to statistics (62-02) Research exposition (monographs, survey articles) pertaining to biology (92-02)

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(11)

• Towards understanding the instrumental variables methods in biometrics and econometrics
• Using ascertainment for targeted resequencing to increase power to identify causal variants
• A modified debiased inverse-variance weighted estimator in two-sample summary-data Mendelian randomization
• Estimating time-varying exposure effects through continuous-time modelling in Mendelian randomization
• A Ridge-Regularized Jackknifed Anderson-Rubin Test
• Mendelian randomization. Methods for using genetic variants in causal estimation
• Mendelian randomization methods for causal inference: estimands, identification and inference
• Nonparametric Bayesian adjustment of unmeasured confounders in Cox proportional hazards models
• An asymptotically optimal two-sample instrumental variables estimation using many instruments
• Estimation of a genetic Gaussian network using GWAS summary data
• Mendelian randomization as an instrumental variable approach to causal inference

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