MethScope

Last update 26 August 2026

Copyright license GNU Affero General Public License, version 3.0

Software version identifier 1.0.0, 1.0.1, 1.0.2, 1.0.3, PACKAGES.rds, 1.0.4

Description

Methods for analyzing DNA methylation data via Most Recurrent Methylation Patterns (MRMPs). Supports cell-type annotation, spatial deconvolution, unsupervised clustering, and cancer cell-of-origin inference. Includes C-backed summaries for YAME ".cg/.cm" files (overlap counts, log2 odds ratios, beta/depth aggregation), an XGBoost classifier, NNLS deconvolution, and plotting utilities. Scales to large spatial and single-cell methylomes and is robust to extreme sparsity.

This page was built for software: MethScope