mfp2

MaRDI QIDQ5980075CRANFDO

Authors Edwin Kipruto, Michael Kammer, Patrick Royston, Willi Sauerbrei

Last update 14 November 2023

Copyright license GNU General Public License, version 3.0

Software version identifier 1.0.0

Description

Multivariable fractional polynomial algorithm simultaneously selects variables and functional forms in both generalized linear models and Cox proportional hazard models. Key references for this algorithm are Royston and Altman (1994)<doi:10.2307/2986270> and Sauerbrei and Royston (2008, ISBN:978-0-470-02842-1). In addition, it can model a 'sigmoid' relationship between variable x and an outcome variable y using the approximate cumulative distribution transformation proposed by Royston (2014) <doi:10.1177/1536867X1401400206>. This feature distinguishes it from a standard fractional polynomial function, which lacks the ability to achieve such modeling.

Cites work

• Regression Using Fractional Polynomials of Continuous Covariates: Parsimonious Parametric Modelling
• A Smooth Covariate Rank Transformation for Use in Regression Models with a Sigmoid Dose–Response Function

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